Motif ID: DMAP1_NCOR{1,2}_SMARC.p2

Z-value: 2.087


Transcription factors associated with DMAP1_NCOR{1,2}_SMARC.p2:

Gene SymbolEntrez IDGene Name
DMAP1 55929 DNA methyltransferase 1 associated protein 1
NCOR1 9611 nuclear receptor co-repressor 1
NCOR2 9612 nuclear receptor co-repressor 2
SMARCA1 6594 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA5 8467 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCC2 6601 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SMARCC2chr12_-_54869511-0.572.6e-02Click!
NCOR2chr12_-_123617962-0.411.3e-01Click!
NCOR1chr17_-_160386070.401.4e-01Click!
DMAP1chr1_+_444516980.253.7e-01Click!
SMARCA1chrX_-_1284851210.214.5e-01Click!
SMARCA5chr4_+_144654005-0.117.1e-01Click!


Activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2.

activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2


Sorted Z-values histogram for motif DMAP1_NCOR{1,2}_SMARC.p2

Sorted Z-values for motif DMAP1_NCOR{1,2}_SMARC.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DMAP1_NCOR{1,2}_SMARC.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_52159143 6.059 NM_002190
IL17A
interleukin 17A
chr15_+_42815851 5.317 NM_080745
NM_182985
TRIM69

tripartite motif containing 69

chr16_+_48865521 4.698 ADCY7
adenylate cyclase 7
chr3_+_120799411 4.510 NM_015900
PLA1A
phospholipase A1 member A
chr16_-_28425632 4.005 NM_145659
IL27
interleukin 27
chr7_+_73826244 3.825 NM_000265
NCF1
NCF1B
NCF1C
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
neutrophil cytosolic factor 1C pseudogene
chr1_+_165564904 3.630 NM_001198783
POU2F1
POU class 2 homeobox 1
chrX_+_78087484 3.505 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr17_-_31231421 3.441 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr6_-_108252200 3.338 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr1_-_111848265 3.287 NM_000677
NM_020683
ADORA3

adenosine A3 receptor

chr1_+_245646080 3.246 NM_001079821
NM_001127461
NLRP3

NLR family, pyrin domain containing 3

chr19_-_55104875 3.195 NUP62
nucleoporin 62kDa
chr1_+_165565006 3.151 POU2F1
POU class 2 homeobox 1
chr6_-_36412562 3.032 NM_001010903
C6orf222
chromosome 6 open reading frame 222
chr17_+_22823151 3.020 NM_014238
KSR1
kinase suppressor of ras 1
chr22_+_38652555 3.006 GRAP2
GRB2-related adaptor protein 2
chr5_-_138753443 2.984 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr1_-_181889070 2.804 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr3_-_3127057 2.693 NM_000564
NM_175724
NM_175725
NM_175726
NM_175727
NM_175728
IL5RA





interleukin 5 receptor, alpha





chr5_-_169657395 2.676 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr5_-_169657312 2.671 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr7_+_106293112 2.635 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr6_-_30188845 2.613 NM_007028
TRIM31
tripartite motif containing 31
chr1_+_156416360 2.577 NM_001766
CD1D
CD1d molecule
chr1_+_40635058 2.572 NM_001198980
SMAP2
small ArfGAP2
chr6_+_158653679 2.569 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr10_-_11614279 2.515 NM_001080491
USP6NL
USP6 N-terminal like
chr2_+_102401580 2.473 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr4_-_40211324 2.431 RBM47
RNA binding motif protein 47
chr19_-_10074332 2.298 NM_031917
ANGPTL6
angiopoietin-like 6
chr5_-_169657192 2.298 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_+_67404756 2.292 NM_144701
IL23R
interleukin 23 receptor
chr19_+_17723285 2.273 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr14_+_99601498 2.231 NM_016337
EVL
Enah/Vasp-like
chr1_+_32489426 2.218 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr16_-_88358946 2.191 FANCA
Fanconi anemia, complementation group A
chr6_+_31647854 2.175 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr14_+_99601517 2.171 EVL
Enah/Vasp-like
chr13_-_102517196 2.166 NM_000452
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter family), member 2
chr5_-_169657360 2.162 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr21_-_33107813 2.155 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr1_-_205161821 2.144 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr11_+_71387572 2.125 NM_001039659
NM_001039660
NM_173042
IL18BP


interleukin 18 binding protein


chr10_+_35466715 2.123 NM_183011
NM_183012
CREM

cAMP responsive element modulator

chr9_-_116732403 2.099 NM_001244
TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
chr10_+_5812616 2.091 C10orf18
chromosome 10 open reading frame 18
chr3_+_2528272 2.089 CNTN4
contactin 4
chr13_+_42034871 2.083 NM_033012
TNFSF11
tumor necrosis factor (ligand) superfamily, member 11
chr22_-_25205376 2.030 NM_152841
HPS4
Hermansky-Pudlak syndrome 4
chr12_-_10173947 2.022 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr1_+_157441824 1.997 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr1_-_205186330 1.975 NM_002644
PIGR
polymeric immunoglobulin receptor
chr10_-_95231933 1.949 NM_013451
NM_133337
MYOF

myoferlin

chr17_-_1195096 1.897 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr10_+_17312654 1.890 VIM
vimentin
chr6_+_31731647 1.888 NM_019101
APOM
apolipoprotein M
chr1_+_32512298 1.875 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr18_+_3441589 1.872 NM_170695
NM_173210
TGIF1

TGFB-induced factor homeobox 1

chr5_-_142795269 1.772 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr1_-_159099090 1.673 NM_001166663
NM_001166664
NM_016382
CD244


CD244 molecule, natural killer cell receptor 2B4


chr19_-_40925151 1.664 NM_024660
TMEM149
transmembrane protein 149
chr6_+_31731667 1.649 APOM
apolipoprotein M
chr7_+_128795178 1.620 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr1_-_205210567 1.619 NM_001122979
NM_001170631
NM_032029
FCAMR


Fc receptor, IgA, IgM, high affinity


chr3_+_123279439 1.618 NM_006889
CD86
CD86 molecule
chr1_+_157441133 1.618 NM_002036
DARC
Duffy blood group, chemokine receptor
chrX_+_110252960 1.598 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr2_-_100125402 1.575 NM_002285
AFF3
AF4/FMR2 family, member 3
chr4_+_38740246 1.573 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr9_-_21340885 1.530 NM_021002
IFNA6
interferon, alpha 6
chr19_-_18369407 1.520 NM_145256
LRRC25
leucine rich repeat containing 25
chr12_+_49922592 1.470 DAZAP2
DAZ associated protein 2
chr22_+_38627031 1.466 NM_004810
GRAP2
GRB2-related adaptor protein 2
chr2_-_207291364 1.448 NM_001093730
DYTN
dystrotelin
chr11_+_60626505 1.444 NM_014207
CD5
CD5 molecule
chr3_+_188568861 1.437 NM_022147
RTP4
receptor (chemosensory) transporter protein 4
chr11_+_63060848 1.431 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr10_+_50177192 1.422 NM_001135196
NM_199459
C10orf71

chromosome 10 open reading frame 71

chr12_+_5023345 1.397 NM_002234
KCNA5
potassium voltage-gated channel, shaker-related subfamily, member 5
chr7_+_128795280 1.380 AHCYL2
adenosylhomocysteinase-like 2
chr14_-_88948486 1.356 FOXN3
forkhead box N3
chr9_+_126460511 1.352


chr1_+_158063130 1.324 SLAMF8
SLAM family member 8
chr7_-_115458047 1.296 TFEC
transcription factor EC
chr14_-_23752875 1.266 NM_014169
CHMP4A
chromatin modifying protein 4A
chr11_-_117718532 1.265 NM_000732
NM_001040651
CD3D

CD3d molecule, delta (CD3-TCR complex)

chr4_-_87500201 1.261 MAPK10
mitogen-activated protein kinase 10
chr6_-_76259976 1.257 NM_015687
FILIP1
filamin A interacting protein 1
chr7_-_86433139 1.249 NM_152748
KIAA1324L
KIAA1324-like
chr12_-_9777126 1.236 NM_172004
CLECL1
C-type lectin-like 1
chr20_+_56919233 1.225 GNAS
GNAS complex locus
chr1_+_158063278 1.219 SLAMF8
SLAM family member 8
chrX_-_131401319 1.217 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr7_-_115458064 1.206 TFEC
transcription factor EC
chr9_-_139047112 1.203 NM_004479
FUT7
fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
chrX_+_119379967 1.176 NM_001142447
NM_012069
ATP1B4

ATPase, Na+/K+ transporting, beta 4 polypeptide

chr1_-_165754325 1.173 NM_000734
NM_198053
CD247

CD247 molecule

chr2_+_143603368 1.170 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr1_+_196874839 1.167 PTPRC
protein tyrosine phosphatase, receptor type, C
chrX_+_117410693 1.158 WDR44
WD repeat domain 44
chr2_+_169637255 1.136 NM_001142270
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr16_-_4778317 1.129 NM_001154458
NM_144605
SEPT12

septin 12

chr3_+_45902999 1.129 NM_006641
NM_031200
CCR9

chemokine (C-C motif) receptor 9

chr4_-_186970366 1.118 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr14_-_106184988 1.117 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_-_115458010 1.114 NM_001018058
NM_012252
TFEC

transcription factor EC

chrX_-_30505804 1.111 NM_025159
CXorf21
chromosome X open reading frame 21
chr13_-_25687062 1.110 RNF6
ring finger protein (C3H2C3 type) 6
chr3_+_46386636 1.100 NM_000579
NM_001100168
CCR5

chemokine (C-C motif) receptor 5

chr9_-_138762725 1.095 NM_198946
LCN6
lipocalin 6
chr2_+_143603439 1.090 ARHGAP15
Rho GTPase activating protein 15
chr2_+_228045053 1.084 AGFG1
ArfGAP with FG repeats 1
chr21_+_42697058 1.082 NM_001001895
NM_018961
UBASH3A

ubiquitin associated and SH3 domain containing A

chr16_+_10878539 1.071 NM_000246
CIITA
class II, major histocompatibility complex, transactivator
chr21_-_35181956 1.066 RUNX1
runt-related transcription factor 1
chr1_-_198643885 1.060 ZNF281
zinc finger protein 281
chr17_-_78000890 1.059 NM_001193655
C17orf62
chromosome 17 open reading frame 62
chr11_+_71388310 1.059 NM_001145057
IL18BP
interleukin 18 binding protein
chr7_+_77307382 1.054 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr8_-_102872372 1.047 NCALD
neurocalcin delta
chr3_-_171070314 1.043 NM_024727
LRRC31
leucine rich repeat containing 31
chr1_-_246869181 1.041 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr19_+_40895669 1.030 NM_014383
ZBTB32
zinc finger and BTB domain containing 32
chr3_-_114176401 1.023 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr21_+_42792810 1.022 NM_018964
SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr17_-_31441390 1.022 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr14_+_75058518 1.009 NM_006399
BATF
basic leucine zipper transcription factor, ATF-like
chr8_-_102872354 1.003 NCALD
neurocalcin delta
chr1_-_153098811 0.996 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr2_-_74606819 0.994 NM_133637
DQX1
DEAQ box RNA-dependent ATPase 1
chr18_-_72820939 0.986 MBP
myelin basic protein
chr12_+_119562737 0.982 NM_001033677
CABP1
calcium binding protein 1
chr20_-_34707971 0.975 NM_032214
NM_175077
SLA2

Src-like-adaptor 2

chr14_-_106202262 0.975 IGLJ3
IGHA1
immunoglobulin lambda joining 3
immunoglobulin heavy constant alpha 1
chr12_+_91620749 0.964 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr12_+_25096472 0.962 NM_006152
LRMP
lymphoid-restricted membrane protein
chr5_-_157011665 0.955


chr1_-_166149867 0.949 NM_001167749
NM_018417
ADCY10

adenylate cyclase 10 (soluble)

chr6_-_149847809 0.947 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr4_-_164614335 0.939 NM_032136
TKTL2
transketolase-like 2
chr2_-_166359016 0.936 NM_004482
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr6_-_149847718 0.932 ZC3H12D
zinc finger CCCH-type containing 12D
chr2_-_74424041 0.924 NM_133478
SLC4A5
solute carrier family 4, sodium bicarbonate cotransporter, member 5
chr14_+_69307914 0.924 SRSF5
serine/arginine-rich splicing factor 5
chr7_+_28418668 0.916 NM_182898
CREB5
cAMP responsive element binding protein 5
chr12_-_8584658 0.911 NM_014358
CLEC4E
C-type lectin domain family 4, member E
chr11_+_118259684 0.905 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr18_+_13601664 0.898 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr22_+_38627129 0.896 GRAP2
GRB2-related adaptor protein 2
chr16_+_24475129 0.896 RBBP6
retinoblastoma binding protein 6
chr1_+_173111306 0.892 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr3_-_58175437 0.889 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr1_+_154386358 0.886 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr3_+_112743615 0.873 NM_005816
NM_198196
CD96

CD96 molecule

chr6_+_99389318 0.863 POU3F2
POU class 3 homeobox 2
chr6_+_44076281 0.861 NM_001171992
NM_153246
C6orf223

chromosome 6 open reading frame 223

chr7_-_129379947 0.848 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

chr1_+_196874759 0.844 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr2_+_218641982 0.841 NM_198483
RUFY4
RUN and FYVE domain containing 4
chr1_+_160868822 0.835 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr22_-_16080265 0.825 CECR1
cat eye syndrome chromosome region, candidate 1
chrX_-_18282698 0.815 NM_006089
SCML2
sex comb on midleg-like 2 (Drosophila)
chr10_-_105208634 0.814 NM_001001412
CALHM1
calcium homeostasis modulator 1
chr14_-_105796268 0.814 ZCWPW2
IGHV3-23
IGKV3-20
zinc finger, CW type with PWWP domain 2
immunoglobulin heavy variable 3-23
immunoglobulin kappa variable 3-20
chr9_-_21218132 0.807 NM_021268
IFNA17
interferon, alpha 17
chr6_-_63053811 0.792 NM_152688
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr12_-_119961143 0.791 NM_003733
NM_198213
OASL

2'-5'-oligoadenylate synthetase-like

chr3_+_179759181 0.787 NM_005832
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr4_-_87500398 0.783 NM_138980
NM_138982
MAPK10

mitogen-activated protein kinase 10

chr1_-_210654858 0.778 TMEM206
transmembrane protein 206
chr1_+_163780063 0.774 NM_001005214
LRRC52
leucine rich repeat containing 52
chr2_-_215711313 0.772 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr11_+_59001421 0.767 NM_001004705
OR4D10
olfactory receptor, family 4, subfamily D, member 10
chr1_+_156526182 0.766 NM_001765
CD1C
CD1c molecule
chr10_-_69125932 0.765 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr1_-_210654862 0.759 NM_001198862
NM_018252
TMEM206

transmembrane protein 206

chr18_+_19706979 0.753 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr4_+_147316284 0.743 NM_007080
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_+_160868932 0.739 DDR2
discoidin domain receptor tyrosine kinase 2
chr18_-_41923571 0.738 ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr9_+_37110506 0.737 ZCCHC7
zinc finger, CCHC domain containing 7
chr6_+_36773605 0.733 RAB44
RAB44, member RAS oncogene family
chr19_-_1046373 0.732 POLR2E
polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
chr7_+_139750311 0.730 NM_001008749
RAB19
RAB19, member RAS oncogene family
chr16_-_49272741 0.727 NM_001144972
NM_153337
NM_182854
SNX20


sorting nexin 20


chr18_-_28606839 0.726 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr2_-_136311219 0.724 NM_002299
LCT
lactase
chr9_+_37110468 0.722 NM_032226
ZCCHC7
zinc finger, CCHC domain containing 7
chr2_+_68855436 0.720 NM_001166276
NM_014882
ARHGAP25

Rho GTPase activating protein 25

chr8_-_103735194 0.716 NM_001032282
KLF10
Kruppel-like factor 10
chr19_-_46504831 0.714


chr5_+_70787371 0.713 BDP1
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
chr8_-_38324809 0.709 WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
chr2_-_152538694 0.707 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr21_-_31995972 0.701 SCAF4
SR-related CTD-associated factor 4
chr19_-_44518465 0.701 GMFG
glia maturation factor, gamma
chr17_+_55854636 0.696 NM_181707
C17orf64
chromosome 17 open reading frame 64
chr17_-_35327318 0.695 NM_018530
GSDMB
gasdermin B
chr7_+_94135384 0.694 PEG10
paternally expressed 10

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.77 8.39e-08 GO:0002376 immune system process
2.01 1.67e-07 GO:0006955 immune response
2.46 5.63e-04 GO:0045321 leukocyte activation
2.58 1.76e-03 GO:0046649 lymphocyte activation
3.00 4.29e-03 GO:0042110 T cell activation
1.95 4.91e-03 GO:0050776 regulation of immune response
1.89 5.04e-03 GO:0001775 cell activation
1.19 6.53e-03 GO:0050896 response to stimulus
1.33 7.29e-03 GO:0048518 positive regulation of biological process
1.66 7.83e-03 GO:0006952 defense response
2.02 7.91e-03 GO:0045087 innate immune response
1.34 1.43e-02 GO:0048522 positive regulation of cellular process
3.54 3.36e-02 GO:0034340 response to type I interferon
1.67 3.54e-02 GO:0002682 regulation of immune system process

Nothing significant found in compartment category.

Nothing significant found in function category.